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Shortages of drugs used to ventilate COVID-19 patients

#342 of 1611 articles from the Special Report: Coronavirus in Canada
electron microscope image, new coronavirus, colorized blue,
This 2020 electron microscope image made available by the U.S. CDC shows the spherical particles of the new coronavirus, colorized blue, from the first U.S. case of COVID-19. File photo by Hannah A. Bullock, Azaibi Tamin/CDC via AP

Emergency doctors have been warned to try to avoid using the limited supply of medications needed for patients on ventilators, as they could be critical in the fight against COVID-19.

Putting a patient on an artificial breathing machine, as happens with people severely sick with COVID-19, usually requires a sedative such as propofol, and painkillers such as fentanyl and morphine.

The Canadian Association of Emergency Physicians wrote a statement to members, warning them of potential shortages of those drugs and their responsibility for conserving them.

"These medications are increasingly used in the emergency department, in addition to their traditional use in the OR and ICU," the association wrote. "As such, emergency physicians have some agency with respect to their use and increasing responsibility for their stewardship."

Propofol and morphine shortages have already been reported to Health Canada by some manufacturers in the last week.

Emergency doctors urged to avoid drugs used to ventilate COVID-19 patients

The association warned Canada's shortage could become critical in weeks.

"This would have significant clinical impact and therefore requires immediate investigation and action," the association wrote in a statement.

There are fears a shortage of the drugs could aggravate a dreaded scenario in which ICUs are flooded with critical COVID-19 patients.

Emergency doctors have been warned to try to safeguard the limited supply by looking for alternative medications and reducing waste.

The group has called on federal and provincial governments to review the existing stock and keep doctors informed.

They also suggest the government needs to manage the national supply of those vital drugs, and create incentives for domestic production to avoid shortages.

Countries around the world have grappled with drug shortages, as the virus has wrought havoc on manufacturing plants and distribution.

The Public Health Agency of Canada and Procurement Canada are working to secure a steady supply of essential medications, needed for daily use as well as the treatment of COVID-19, the prime minister said Wednesday.

"We have very strong relationships around the world on getting medication and necessary supplies," Justin Trudeau said.

He said the government is doing everything it can to make sure hospitals and patients have what they need.

This report by The Canadian Press was first published April 15, 2020.

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